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ACROBiosystems Human IL-18BP Protein, His Tag

MALS verified

Marke:  ACROBiosystems ILP-H5222-1MG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15827107

  • 1013.29 CHF / 1 Milligramm


Verfügbar ab
04-06-2021
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Beschreibung

Beschreibung

Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL-18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.5 kDa. The protein migrates as 32-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_001138529
HEK293
Human
18.5 kDa
1 mg
Thr 31 - Gly 194
IL18BP,IL18BPa,Tadekinig-alfa
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>90% as determined by SDS-PAGE
Human IL-18 BP, His Tag (ILP-H5222) is expressed from human 293 cells (HEK293). It contains AA Thr 31 - Gly 194 (Accession # NP_001138529).
-20°C
IL-18 BP
His Tag
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Sicherheitsdatenblatt (SDS)
Dokumentation