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ACROBiosystems Human IL-18BP Protein, His Tag
MALS verified
315.25 CHF - 1235.79 CHF
Spezifikation
Zugriffsnummer | NP_001138529 |
---|---|
Molekulargewicht | 18.5 kDa |
Quelle | Human IL-18 BP, His Tag (ILP-H5222) is expressed from human 293 cells (HEK293). It contains AA Thr 31 - Gly 194 (Accession # NP_001138529). |
Immunogen | Thr 31 - Gly 194 |
Lagerungsbedingungen | -20°C |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15837107
|
ACROBiosystems
ILP-H5222-200UG |
200 μg |
315.25 CHF
200 Mikrogramm |
Verfügbar ab: 17-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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15827107
|
ACROBiosystems
ILP-H5222-1MG |
1 mg |
1235.79 CHF
1 Milligramm |
Verfügbar ab: 17-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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Beschreibung
Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL-18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.5 kDa. The protein migrates as 32-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_001138529 | |
Human IL-18 BP, His Tag (ILP-H5222) is expressed from human 293 cells (HEK293). It contains AA Thr 31 - Gly 194 (Accession # NP_001138529). | |
-20°C | |
IL-18 BP | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Bio-Markers and CD Antigens |
18.5 kDa | |
Thr 31 - Gly 194 | |
IL18BP,IL18BPa,Tadekinig-alfa | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |