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Abnova™ Human GUCA1A Partial ORF (NP_000400, 1 a.a. - 93 a.a.) Recombinant Protein with GST-tag at N-terminal

Used for AP, Array, ELISA, WB-Re

361.00 CHF - 547.00 CHF

Spezifikation

Zugriffsnummer NP_000400
Zur Verwendung mit (Anwendung) Antibody Production, ELISA, Protein Array, Western Blot
Zusammensetzung 50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer.
Gen-ID (Entrez) 2978
Molekulargewicht 35.97kDa
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
16129084
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Abnova™
H00002978-Q01.10UG
10 ug
361.00 CHF
10 Mikrogramm
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Verfügbar ab: 03-06-2024
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16139084
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Abnova™
H00002978-Q01.25UG
25 ug
547.00 CHF
25 Mikrogramm
Ver productos alternativos
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Verfügbar ab: 03-06-2024
Sie sich ein, um den Lagerbestand zu sehen
Añadir a la cesta
 
Descripción

Descripción

This gene plays a role in the recovery of retinal photoreceptors from photobleaching. In the recovery phase, the phototransduction messeneger cGMP is replenished by retinal guanylyl cyclase-1 (GC1). GC1 is activated by decreasing Ca(2+) concentrations following photobleaching. The protein encoded by this gene, guanylyl cyclase activating protein 1 (GCAP1), mediates the sensitivity of GC1 to Ca(2+) concentrations. GCAP1 promotes activity of GC1 at low Ca(2+) concentrations and inhibits GC1 activity at high Ca(2+) concentrations. Mutations in this gene cause autosomal dominant cone dystrophy (COD3); a disease characterized by reduced visual acuity associated with progressive loss of color vision. Mutations in this gene prohibit the inactivation of RetGC1 at high Ca(2+) concentrations; causing the constitutive activation of RetGC1 and, presumably, increased cell death. This gene is expressed in retina and spermatagonia. [provided by RefSeq]

Sequence: MGNVMEGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLR
Especificaciones

Especificaciones

NP_000400
50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer.
35.97kDa
12.5% SDS-PAGE Stained with Coomassie Blue.
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
COD3/GCAP/GCAP1/GUCA/GUCA1
GUCA1A
Recombinant
wheat germ expression system
Antibody Production, ELISA, Protein Array, Western Blot
2978
GUCA1A (Human) Recombinant Protein (Q01)
MGNVMEGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLR
RUO
GUCA1A
Wheat Germ (in vitro)
GST
Liquid
Videos
SDS
Documentos

Documentos

Certificados