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Invitrogen™ Human Fc gamma RIIIA (CD16a) (176 Phe) His-tag, Recombinant Protein

HEK293 cells Recombinant Protein

78.50 CHF - 247.00 CHF

Spezifikation

Zugriffsnummer O75015, P08637
Zur Verwendung mit (Anwendung) Control, ELISA, Immunohistochemistry, Western Blot
Zusammensetzung protein; pH 7.4
Gen-ID (Entrez) 2214, 2215
Name Human Fc gamma RIIIA (CD16a) (176 Phe) His-tag
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
17114213
Unterlagen ansehen Aktionsdetails
Invitrogen™
A42538
50 μg
247.00 CHF
50 Mikrogramm
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Verfügbar ab: 30-04-2024
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17104213
Unterlagen ansehen Aktionsdetails
Invitrogen™
A42537
5 μg Dieser Artikel wurde eingestellt und ist leider nicht mehr verfügbar. Sehen Sie sich das Produkt an, um alternative Produktvorschläge zu sehen oder kontaktieren Sie unseren Technischen Support unter 056 618 41 11.
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Beschreibung

Beschreibung

CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FCGR3A is associated, with FcepsilonRI-beta subunit. Besides IgG, FCGR3A can be triggered also by oligomeric IgE. FCGR3B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a pro-adhesive phenotype. Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.
Spezifikation

Spezifikation

O75015, P08637
protein; pH 7.4
Human Fc gamma RIIIA (CD16a) (176 Phe) His-tag
-20°C
<1 EU/μg
FCGR3A, FCGR3B
Unconjugated
Lyophilized
Control, ELISA, Immunohistochemistry, Western Blot
2214, 2215
HEK293 cells
RUO
4833442P21Rik; CD16; CD16-2; CD16A; CD16a antigen; CD16B; CD32; CD32 receptor 2; CDw32; cytolytic trigger molecule G7; Fc fragment of IgG intermediate affinity IV receptor; Fc fragment of IgG low affinity IIIa receptor; Fc fragment of IgG receptor IIIa; Fc fragment of IgG receptor IIIb; Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor III; Fc gamma receptor IIIa; Fc gamma receptor III-A; Fc gamma receptor IIIb; Fc gamma RIIIa; Fc gammaRIV; Fc receptor, IgG, low affinity III; Fc receptor, IgG, low affinity IV; Fc receptor-like 3; Fcg receptor III; FCG2; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD 16);
Human
Recombinant
≥ 90%
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