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ACROBiosystems Human DNAM-1 / CD226 Protein, His Tag
Marke: ACROBiosystems DN1-H52H6-1MG
Additional Details : Gewicht : 0.00001kg
Beschreibung
DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ∼65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 36-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_006557 | |
1 mg | |
Glu 19 - Asn 247 | |
DNAM1,CD226,PTA1 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
27.9 kDa | |
Human DNAM-1, His Tag (DN1-H52H6) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Asn 247 (Accession # NP_006557). | |
-20°C | |
DNAM-1 | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Immune Checkpoint Proteins |