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ACROBiosystems Human CXADR / CAR Protein, His Tag
315.25 CHF - 2017.60 CHF
Spezifikation
Zugriffsnummer | NP_001329.1 |
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Molekulargewicht | 24.9 kDa |
Quelle | Human CXADR, His Tag (CXR-H5222) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Gly 237 (Accession # NP_001329.1). |
Immunogen | Leu 20 - Gly 237 |
Lagerungsbedingungen | -20°C |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15826557
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ACROBiosystems
CXR-H5222-1MG |
1 mg |
2017.60 CHF
1 Milligramm |
Verfügbar ab: 17-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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15816557
|
ACROBiosystems
CXR-H5222-100UG |
100 μg |
315.25 CHF
100 Mikrogramm |
Verfügbar ab: 17-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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Beschreibung
Coxsackie virus and adenovirus receptor (CXADR) is also known as CAR, is a type I transmembrane glycoprotein for group B coxsackie viruses and subgroup C adenoviruses, and belongs to the CTX family of the Ig superfamily. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins such as: fibronectin, agrin, laminin-1 and tenascin-R. Human CXADR protein contains a signal sequence, a extracellular domain (ECD) with a V type (D1) and a C2 type (D2) Iglike domain, a transmembrane segment and a intracellular domain. D1 is thought to be responsible for homodimer formation in trans within tight junctions, and is necessary and sufficient for adenovirus binding. Variants of CXADR are attached to the cell membrane by a GPI- anchor.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.9 kDa. The protein migrates as 32-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_001329.1 | |
Human CXADR, His Tag (CXR-H5222) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Gly 237 (Accession # NP_001329.1). | |
-20°C | |
CXADR | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Other Recombinant Proteins |
24.9 kDa | |
Leu 20 - Gly 237 | |
CXADR,CAR,CAR4/6,HCAR | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |