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ACROBiosystems Human CD58 / LFA-3 Protein, His Tag

Marke:  ACROBiosystems LF3-H5225-100UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15817247

  • 322.42 CHF / 100 Mikrogramm


Verfügbar ab
28-05-2021
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Beschreibung

Beschreibung

CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22.3 kDa. The protein migrates as 30-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

AAH05930
HEK293
Human
22.3 kDa
100 µg
Phe 29 - Arg 215
CD58,LFA3,Ag3
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Human CD58, His Tag (LF3-H5225) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Arg 215 (Accession # AAH05930).
-20°C
CD58
His Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation