Learn More
ACROBiosystems Human CD31 / PECAM-1 Protein, His Tag
315.25 CHF - 2017.60 CHF
Spezifikation
Zugriffsnummer | NP_000433.4 |
---|---|
Molekulargewicht | 66.4 kDa |
Quelle | Human CD31, His Tag (CD1-H5224) is expressed from human 293 cells (HEK293). It contains AA Gln 28 - Lys 601 (Accession # P16284-1). |
Immunogen | Gln 28 - Lys 601 |
Lagerungsbedingungen | -20°C |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
---|---|---|---|---|---|---|---|---|---|
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15826147
|
ACROBiosystems
CD1-H5224-1MG |
1 mg |
2017.60 CHF
1 Milligramm |
Verfügbar ab: 30-04-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
|||||
15816147
|
ACROBiosystems
CD1-H5224-100UG |
100 μg |
315.25 CHF
100 Mikrogramm |
Verfügbar ab: 30-04-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
|||||
Beschreibung
Cluster of Differentiation 31 (CD31) is also known as Platelet endothelial cell adhesion molecule (PECAM-1), is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, osteoclasts, neutrophils, certain tumors, and is the only known member of the CAM family on platelets. CD31 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. CD31 plays a key role in removing aged neutrophils from the body. CD31 mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. In addition, it has been shown that CD31 expression is up-regulated by LPS stimulation, and might function as a feedback negative regulator of LPS inflammatory response in macrophages.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 66.4 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_000433.4 | |
Human CD31, His Tag (CD1-H5224) is expressed from human 293 cells (HEK293). It contains AA Gln 28 - Lys 601 (Accession # P16284-1). | |
-20°C | |
CD31 | |
Human | |
50 mM Tris, 150 mM NaCl, pH7.5 | |
HEK293 | |
Bio-Markers and CD Antigens |
66.4 kDa | |
Gln 28 - Lys 601 | |
PECAM1,CD31,FLJ34100,FLJ58394 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |