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ACROBiosystems Human BTN1A1 / Butyrophilin Protein, Fc Tag

Marke:  ACROBiosystems BT1-H5253-100UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15826057

  • 333.92 CHF / 100 Mikrogramm


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27-05-2021
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Beschreibung

Beschreibung

Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.6 kDa. As a result of glycosylation, the protein migrates as 55-66 kDa under reducing (R) condition, and 116-130 kDa under non-reducing (NR) condition (SDS-P
Spezifikation

Spezifikation

AAH96312
HEK293
Human
50.6 kDa
100 µg
Ala 27 - Arg 242
BTN1A1,Butyrophilin,BTN
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>95% as determined by SDS-PAGE
Human BTN1A1, Fc Tag (BT1-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Arg 242 (Accession # AAH96312).
-20°C
BTN1A1
Fc Tag
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