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ACROBiosystems Human B7-H3 / CD276 Protein, His Tag

MALS verified

Marke:  ACROBiosystems B73-H52E2-100UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15825957

  • 333.92 CHF / 100 Mikrogramm


Verfügbar ab
26-05-2021
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Beschreibung

Beschreibung

B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.2 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>95% as determined by SDS-PAGE
Human B7-H3, His Tag (B73-H52E2) is expressed from human 293 cells (HEK293). It contains AA Leu 29 - Pro 245 (Accession # Q5ZPR3-2).
-20°C
B7-H3
His Tag
HEK293
Human
25.2 kDa
100 µg
Leu 29 - Pro 245
B7-H3,CD276,B7 homolog 3
Unconjugated
PBS, pH7.4
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation