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Cytiva HiTrap™ MabSelect SuRe™ PCC Columns
Prepacked with MabSelect SuRe™ PCC Protein A Resin for screening and small-scale mAb purification in continuous bioprocessing using periodic counter-current chromatography (PCC)
1081.00 CHF
Spezifikation
Beschreibung | Fließgeschwindigkeit: ≤ 600 cm/h |
---|---|
Produkttyp | Chromatographiesäule |
Höhe (metrisch) | 25 mm |
Max. Druck | 5 bar (0,5 MPa) |
Inhalt und Lagerung | Lagerung bei 2 bis 8 °C, 20 % Ethanol |
Beschreibung
- Suited for small scale antibody purifications, as well as optimization of methods and parameters, such as sample load and protein binding conditions
- Alkali-stabilized, protein A-derived ligand gives the resin greater stability than conventional protein A-based resins under the alkaline conditions used in cleaning-in-place (CIP) protocols
- These protein A columns provide fast, reproducible, and easy separations in a convenient format
- Highly concentrated elution pools for operating flexibility and small unit operations
- Allows cost-effective cleaning with 0.1 to 0.5 M NaOH over hundreds of purification cycles
- Efficiently inactivates bacteria, mold, and yeast, with improved product quality as a result
- Columns are optimally utilized when they are connected to liquid chromatography systems such as the ÄKTA systems
- High binding capacity: ∼ 60 mg Human IgG/mL Resin at 2.4 min residence time
Spezifikation
Fließgeschwindigkeit: ≤ 600 cm/h | |
25 mm | |
Lagerung bei 2 bis 8 °C, 20 % Ethanol | |
Affinitätssäule | |
MabSelect SuRe PCC Protein A-Harz |
Chromatographiesäule | |
5 bar (0,5 MPa) | |
∼60 mg Human-IgG/ml Harz | |
Antikörper-Affinitätschromatographie |