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HAAO Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 12791-1-AP-150UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16840694

  • 381.34 CHF / 150 Mikroliter
Verfügbar ab: 16-04-2024
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Beschreibung

Beschreibung

HAAO (3-Hydroxyanthranilate 3, 4-dioxygenase) is a monomeric cytosolic protein of the family of intramolecular dioxygenases containing non-heme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is present in low amounts in the central nervous system. This enzyme participates in tryptophan metabolism. It employs one cofactor, iron. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurological and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. Furthermore, recent study shows that HAAO are excellent candidate biomarkers for detecting ovarian cancer.
Spezifikation

Spezifikation

HAAO
Polyclonal
Unconjugated
HAAO
3 HAO, HAAO, HAD, HAO
Rabbit
Antigen Affinity Chromatography
RUO
107766, 23498, 56823
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.29 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P46952, P46953, Q78JT3
Haao
HAAO Fusion Protein Ag3511
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote