missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Rekombinante Proteine
  4. AcroBiosystems GMP Human IL-4 Protein

AcroBiosystems GMP Human IL-4 Protein

Artikelnummer. 31453222
Ansicht ändern
Click to view available options
Menge:
10 mg
50 μg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Artikelnummer. Menge
31453222 10 mg
31452108 50 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen
Artikelnummer. 31453222 Lieferant AcroBiosystems Lieferanten-Nr. GMPL04H2610mg

Please to purchase this item. Need a web account? Register with us today!

Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen

Beschreibung

Recombinant Protein

Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.

Spezifikation

Zugriffsnummer Uniprot
Charakterisierung IL-4 Structure This protein carries no tag. The protein has a calculated MW of 15.0 kDa. The protein migrates as 19 kDa±3 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Format Powder-GMP
Zusammensetzung Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4 with protectants. Contact us for customized product form or formulation.
Qualitätskontrollen <0.5 ng/μg of protein tested by ELISA.∣<0.02 ng/μg of protein tested by qPCR.∣Less than 10 EU/mg, tested by the LAL method in compliance with USP 85 and Ph. Eur. 2.6.14.∣Sterility testing was performed using the membrane filtration method in compliance with USP &CM and Ph. Eur. 2.6.1.∣Negative
Menge 10 mg
Quelle GMP Human IL-4 Protein (GMP-L04H26) is expressed from human 293 cells (HEK293). It contains AA His 25 - Ser 153 (Accession # ). Predicted N-terminus: His 25 Request for sequence
Biologische Aktivität GMP Human IL-4 Protein (Cat. No. GMP-L04H26) stimulates proliferation of TF-1 human erythroleukemic cell line. The specific activity of GMP Human IL-4 Protein is >1.20x10^7 IU/mg, which is calibrated against human IL-4 WHO International Standard (NIBSC code: 88/656) (QC tested).∣The activity of GMP Human IL-4 Protein (Cat. No. GMP-L04H26) was higher than other competing products.∣The Cell based assay shows that GMP Human IL-4 Protein (Cat. No. GMP-L04H26) is stable at 37°C for 24 hours.∣The Cell based assay shows that GMP Human IL-4 Protein (Cat. No. GMP-L04H26) is stable at 4°C for 180 days.∣The Cell based assay shows that GMP Human IL-4 Protein (Cat. No. GMP-L04H26) is stable after freezing and thawing 3 times.∣The Cell based assay shows batch-to-batch consistency between Acro's GMP and PG IL-4.
Spezies Human
Sterilität Sterile
Inhalt und Lagerung -20°C to -70°C for 5 years in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution. Upon receipt, store it immediately at -20°C or lower for long term storage.
Endotoxin-Gehalt Less than 10 EU/mg, tested by the LAL method in compliance with USP 85 and Ph. Eur. 2.6.14.
Versandbedingung This product is supplied and shipped with blue ice, please inquire the shipping cost.
Spezifische Aktivität The activity of GMP Human IL-4 Protein (Cat. No. GMP-L04H26) was higher than other competing products.
Reinheits- oder Qualitätsgrad 0.95
Mehr anzeigen Weniger anzeigen
Name des Produkts
Wählen Sie ein Thema

Indem Sie auf Absenden klicken, erklären Sie sich damit einverstanden, dass Fisher Scientific sich mit Ihnen in Verbindung setzen kann, um Ihr Feedback in diesem Formular zu bearbeiten. Wir werden Ihre Informationen nicht für andere Zwecke weitergeben. Alle bereitgestellten Kontaktinformationen werden in Übereinstimmung mit unserer Datenschutzrichtlinie aufbewahrt. Datenschutzrichtlinie.