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Invitrogen™ Glutamine Synthetase Polyclonal Antibody
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Artikelnummer. 13473057
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Menge:
100 μL
Packungsgröße:
100 Mikroliter
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13473057 100 μL 100 Mikroliter
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Artikelnummer. 13473057 Lieferant Invitrogen™ Lieferanten-Nr. PA528940

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Beschreibung

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, U87-MG, SK-N-SH, IMR32, SK-N-AS, mouse brain, mouse eye, rat brain. Predicted reactivity: Mouse (94%), Rat (92%), Xenopus laevis (85%), Dog (97%), Pig (96%), Chicken (88%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen Glutamine Synthetase
Anwendungen Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Klassifikation Polyclonal
Konzentration 0.72 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gen GLUL
Gen-Zugriffsnummer P09606, P15104, P15105
Gen-Alias cell proliferation-inducing protein 59; GLNA; GLNS; Glul; GLUL protein; Glutamate ammonia ligase; glutamate decarboxylase; glutamate-ammonia ligase; glutamate--ammonia ligase; glutamate-ammonia ligase (glutamine synthase); glutamate-ammonia ligase (glutamine synthetase); glutamine synthase; glutamine synthetase; Glutamine synthetase (glutamate-ammonia ligase); glutamine synthetase 1; glutamine synthetase I; GS; Palmitoyltransferase GLUL; PIG43; PIG59; Proliferation inducing protein 43; proliferation-inducing protein 43
Gensymbole GLUL
Wirtsspezies Rabbit
Immunogen Full length human Glutamine synthetase Recombinant protein.
Reinigungsverfahren Antigen affinity chromatography
Menge 100 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 14645, 24957, 2752
Zielspezies Human, Mouse, Rat
Inhalt und Lagerung Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotype IgG
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