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Tocris Bioscience™ Genistein
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Artikelnummer. 18712804
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10 mg
50 mg
Packungsgröße:
10 Milligramm
50 Milligramm
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18712804 50 mg 50 Milligramm
18702704 10 mg 10 Milligramm
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Artikelnummer. 18712804 Lieferant Tocris Bioscience™ Lieferanten-Nr. 1110/50

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Description

EGFR kinase inhibitor. Also estrogen and PPARγ ligand

Genistein is a phytoestrogen with a wide range of biological actions. Genistein inhibits protein tyrosine kinases including epidermal growth factor receptor kinase, binds to PPARγ and estrogen receptors and acts as an agonist at GPER. Genistein inhibits aggregation and fibrilization of Aβ42 and amylin37 (hiAPP). In Huntington's disease fibroblast cells, Genistein reduces intracellular mutant huntingtin (mHTT) aggregates and induces degradation of mHTT; in a cellular model of Huntington's disease, Genistein corrects the mutant phenotype through stimulation of autophagy.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 446-72-0
Summenformel C15H10O5

Specifications

Chemischer Name oder Material Genistein
Menge 50 mg
Formelmasse 270.24
Reinheit >98%
Molekulargewicht 270.24
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