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STEMCELL Technologies Genistein

Codice prodotto. 17110012
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Quantità:
100 mg
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Codice prodotto. Quantità
17110012 100 mg
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Codice prodotto. 17110012 Fornitore STEMCELL Technologies N. del fornitore 72002
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Verfügbar ab: 03-12-2026
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Descrizione

NF-kB, AMPK, and tyrosine kinase pathway inhibitor; Inhibits tyrosine kinase, topoisomerase II and activates PPARγ

  • Genistein is a phytoestrogen that exhibits a wide range of biological effects
  • It acts by competing for the ATP-binding site of tyrosine kinases but does not inhibit the activity of serine- and threonine-specific kinases such as cAMP-dependent protein kinase, protein kinase C, and phosphorylase kinase (Akiyama et al.) Genistein binds to and activates peroxisome proliferator-activated receptor-gamma (PPARγ) and estrogen receptors, leading to a decrease in osteogenesis and an increase in adipogenesis (Dang et al.) Genistein also binds and activates the seven-transmembrane estrogen receptor GPR30 to activate alternative estrogen signaling pathways (Thomas & Dong)
  • Inhibits adipocyte differentiation in 3T3-L1 cell culture (Hwang et al.)
  • Control of osteoblast and adipocyte cell fates in mouse bone marrow cells (Dang et al.)
  • Inhibits growth of leukemia, lymphoma, neuroblastoma, gastric, breast, and prostate cancer cells (Sarkar & Li)

Specifica

CAS 446-72-0
Quantità 100 mg
Formula molecolare C15H10O5
Purezza ≥98%
Titolo del prodotto
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