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Geldanamycin, 98+%, Thermo Scientific™
Benzoquinoid antibiotic that inhibits pp60src tyrosine kinase
138.43 CHF - 499.46 CHF
Chemische Identifikatoren
| CAS | 30562-34-6 |
|---|---|
| Summenformel | C29H40N2O9 |
| Molekulargewicht (g/mol) | 560.644 |
| MDL-Nummer | MFCD00274570 |
| InChI-Schlüssel | QTQAWLPCGQOSGP-KDFVLELPSA-N |
| Synonym | NSC 122750; U-29135 |
| PubChem CID | 133688416 |
| IUPAC-Name | [(3S,5R,6S,7R,8Z,11R,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate |
| SMILES | CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15405649
|
Thermo Scientific Alfa Aesar
J63397.MB |
25mg |
138.43 CHF
25 Milligramm |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
|
15415649
|
Thermo Scientific Alfa Aesar
J63397.MC |
100mg |
335.78 CHF
100 Milligramm |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
|
15425649
|
Thermo Scientific Alfa Aesar
J63397.MD |
250mg |
499.46 CHF
250 Milligramm |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
Beschreibung
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
ApplicationsGeldanamycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins. It interferes with conformational maturation of proteins and the cellular stress response. In addition, it is a potent inhibitor of the nuclear hormone receptor family.
Solubility
Soluble in dimethyl sulfoxide at 100 mg/mL.
Notes
Store in a cool dry place. Keep away from oxidizing agents. Protect from heat.
Chemische Identifikatoren
| 30562-34-6 | |
| 560.644 | |
| QTQAWLPCGQOSGP-KDFVLELPSA-N | |
| 133688416 | |
| CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC |
| C29H40N2O9 | |
| MFCD00274570 | |
| NSC 122750; U-29135 | |
| [(3S,5R,6S,7R,8Z,11R,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate |
Spezifikation
| Geldanamycin | |
| Yellow to Orange | |
| MFCD00274570 | |
| Soluble in dimethyl sulfoxide at 100mg/mL. | |
| CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC | |
| 560.644 | |
| 560.64 |
| 30562-34-6 | |
| C29H40N2O9 | |
| NSC 122750; U-29135 | |
| QTQAWLPCGQOSGP-KDFVLELPSA-N | |
| [(3S,5R,6S,7R,8Z,11R,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate | |
| 133688416 | |
| ≥99% |
Sicherheit und Handhabung
missing translation for 'rtecsNumber' : LX8920000
missing translation for 'tsca' : No
Recommended Storage : Store at -20°C
RUO – Research Use Only
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