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GDAP1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 13152-1-AP-20UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16841224

  • 131.19 CHF / 20 Mikroliter

Verfügbar ab: 28-06-2022
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Beschreibung

Beschreibung

Glutathione S-transferases (GSTs) function to conjugate reduced glutathione to many exogenous and endogenous hydrophobic electrophiles. Although it shares the carboxy and amino-terminal glutathione S-transferase domains, GDAP1 (ganglioside-induced differentiation-associated protein 1) is characterized as a GST-like protein because it contains an extended GST domain II and a predicted transmembrane domain, two characteristics which are unusual for GST family members. GDAP1 may function in a signal transduction pathway that is responsible for ganglioside-induced neurite differentiation and also may play a role in protecting myelin membranes from free-radical damage. Mutations in the gene encoding GDAP1 is the cause of many forms of Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system that is characterized by reduced nerve conduction velocities, slow progressive distal muscle atrophy and absent deep tendon reflexes.
Spezifikation

Spezifikation

GDAP1
Polyclonal
Unconjugated
GDAP1
CMTRIA, GDAP1
Rabbit
Antigen Affinity Chromatography
RUO
14545, 54332
Antibody
IgG
Western Blot
0.44 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O88741, Q8TB36
GDAP1
GDAP1 Fusion Protein Ag3769
20 μL
Primary
Human, Mouse
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote