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FR4 Monoclonal Antibody (eBio12A5), PE-Cyanine7, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
243.00 CHF - 536.00 CHF
Spezifikation
Antigen | FR4 |
---|---|
Klon | eBio12A5 |
Konzentration | 0.2 mg/mL |
Anwendungen | Flow Cytometry |
Klassifikation | Monoclonal |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15320970
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Affymetrix eBioscience
25-5445-80 |
25 μg |
243.00 CHF
25 Mikrogramm |
Verfügbar ab: 30-04-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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15330970
|
Affymetrix eBioscience
25-5445-82 |
100 μg |
536.00 CHF
100 Mikrogramm |
Verfügbar ab: 29-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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Beschreibung
Description: The monoclonal antibody eBio12A5 recognizes FR4, also known as Folate receptor 4, FR delta and FBP3 (folate binding protein3). FR4 is a heavily glycosylated, 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural Treg have high levels of FR4 and together with CD25 can be used to distinguish natural Treg, effector T cells, memory-like T cells and naive T cells. FR4 high CD25 high cells are natural Treg with high levels of Foxp3. FR4 high CD25 low cells are identified as central memory T cells, which upon stimulation, can proliferate and produce large amounts of IL-2. In contrast, FR4 low CD25 high cells secrete proinflammatory cytokines such as IFN gamma and IL-17 and have been characterized as effector memory T cells. Based on co-staining studies, the epitopes recognized by eBioTH6 and eBio12A5 are different, thereby allowing functional studies with eBioTH6 to be evaluated with eBio12A5. Applications Reported: This eBio12A5 antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBio12A5 antibody has been tested by flow cytyometric analysis of mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
FR4 Monoclonal antibody specifically detects FR4 in Mouse samples. It is validated for Flow Cytometry.Spezifikation
FR4 | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.09% sodium azide; pH 7.2 | |
0910001L11Rik; C86255; Folate receptor 4; folate receptor 4 (delta); folate receptor 4 (delta) homolog; folate receptor 4, delta (putative); folate receptor delta; Folate-binding protein 3; Folbp3; Folr4; FR-delta; IZUMO1 receptor protein JUNO; IZUMO1 receptor, JUNO; Izumo1r; Juno; probable folate receptor delta; sperm-egg fusion protein Juno | |
Izumo1r | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
Izumo1r |
eBio12A5 | |
Flow Cytometry | |
PE-Cyanine7 | |
Rat | |
Mouse | |
Q9EQF4 | |
64931 | |
IgG2b κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.