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Invitrogen™ Factor X/Xa Monoclonal Antibody (15)
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Artikelnummer. 16383344
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Menge:
100 μL
Packungsgröße:
100 Mikroliter
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16383344 100 μL 100 Mikroliter
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Artikelnummer. 16383344 Lieferant Invitrogen™ Lieferanten-Nr. MA529253

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Beschreibung

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human Coagulation Factor X/F10.

Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen Factor X/Xa
Anwendungen Immunohistochemistry (Paraffin)
Klassifikation Monoclonal
Klon 15
Konzentration 1 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with no preservative
Gen F10
Gen-Zugriffsnummer P00742
Gen-Alias Activated factor Xa heavy chain; blood coagulation factor X; Cf10; coagulation factor 10; coagulation factor X; coagulation factor X protein; F10; Factor X heavy chain; Factor X light chain; factor Xa; FX; FXA; prothrombinase; stuart factor; Stuart-Prower factor; Unknown (protein for IMAGE:8121240); unnamed protein product
Gensymbole F10
Wirtsspezies Mouse
Immunogen Recombinant Human Coagulation Factor X/F10 protein (Met1-Lys488).
Reinigungsverfahren Protein A
Menge 100 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 2159
Zielspezies Human
Inhalt und Lagerung Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotype IgG1
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