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Epstein Barr Virus Nuclear Antigen 1 Polyclonal Antibody, Biotin, Invitrogen™

Goat Polyclonal Antibody

Marke:  Invitrogen PA17499

Additional Details : Gewicht : 0.01000kg

Artikelnummer. 11544260

  • 654.00 CHF / 1 Stück
Verfügbar ab: 04-06-2024
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Beschreibung

Beschreibung

The PA1-7499 antibody reacts with Epstein-Barr virus EBNA-1. PA1-7499 has been successfully used in Immunohistochemical, ELISA, Immunofluorescence and Western blot applications. The PA1-7499 antibody was raised against Recombinant EBV EBNA-1. Store at 4oC for up to 6 months. For long term storage, aliquot and freeze at -20oC. Avoid freeze-thaw cycles.

Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
Spezifikation

Spezifikation

Epstein Barr Virus Nuclear Antigen 1
Polyclonal
Biotin
EBNA-1
Purified recombinant EBV EBNA-1.
1 mL
Primary
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Immunohistochemistry, Western Blot
4-5 mg/mL
PBS with 0.1% sodium azide; pH 7.2
Goat
IgG fraction
RUO
Virus
Antibody
IgG
Produktvorschläge

Produktvorschläge

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Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote