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Epstein Barr Virus Nuclear Antigen 1 Polyclonal Antibody, Biotin, Invitrogen™
Goat Polyclonal Antibody
Marke: Invitrogen PA17499
Additional Details : Gewicht : 0.01000kg
Beschreibung
The PA1-7499 antibody reacts with Epstein-Barr virus EBNA-1. PA1-7499 has been successfully used in Immunohistochemical, ELISA, Immunofluorescence and Western blot applications. The PA1-7499 antibody was raised against Recombinant EBV EBNA-1. Store at 4oC for up to 6 months. For long term storage, aliquot and freeze at -20oC. Avoid freeze-thaw cycles.
Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.Spezifikation
Epstein Barr Virus Nuclear Antigen 1 | |
Polyclonal | |
Biotin | |
EBNA-1 | |
Purified recombinant EBV EBNA-1. | |
1 mL | |
Primary | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
ELISA, Immunohistochemistry, Western Blot | |
4-5 mg/mL | |
PBS with 0.1% sodium azide; pH 7.2 | |
Goat | |
IgG fraction | |
RUO | |
Virus | |
Antibody | |
IgG |