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DTYMK Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Thermo Scientific PA560040
Additional Details : Gewicht : 0.02000kg
Beschreibung
Immunogen sequence: DLVLFLQLQL ADAAKRGAFG HERYENGAFQ ERALRCFHQL MKDTTLNWKM VDASKSIEAV HEDIRVLSED AIRTAT Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 71%.
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.Spezifikation
| DTYMK | |
| Polyclonal | |
| Unconjugated | |
| DTYMK | |
| AU044245; CDC8; D10Ertd203e; deoxythymidylate kinase; deoxythymidylate kinase (thymidylate kinase); dTMP kinase; DTYMK; mtmk; PP3731; Thymidylate kinase; Tmk; TMPK; TYMK; TYPK | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 1841 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry, Western Blot | |
| 0.7 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P23919 | |
| DTYMK | |
| Recombinant protein corresponding to Human DTYMK | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only