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Dobutamine hydrochloride

Artikelnummer. 15463939
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Menge:
250 mg
1 g
Packungsgröße:
1 Gramm
250 Milligramm
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15463939 250 mg 250 Milligramm
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Artikelnummer. 15463939 Lieferant Thermo Scientific Alfa Aesar Lieferanten-Nr. J61333.MD
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Beschreibung

CAS: 49745-95-1 | C18H24ClNO3 | 337.84 g/mol

Dobutamine hydrochloride is a catecholamine that acts as a β-adrenergic receptor agonist. It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions. As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects. It is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1M.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Dobutamine hydrochloride is a catecholamine that acts as a β-adrenergic receptor agonist. It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions. As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects. It is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 μM.

Solubility
Soluble in water or ethanol with warming. Also soluble in methanol

Notes
Solutions oxidize readily at pH greater than 11. Protect solutions from light
TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 49745-95-1
Summenformel C18H24ClNO3
Molekulargewicht (g/mol) 337.84
MDL-Nummer MFCD00153795
InChI-Schlüssel BQKADKWNRWCIJL-UHFFFAOYNA-N
Synonym dobutamine hydrochloride, dobutamine hcl, dobutrex, inotrex, dl-dobutamine hydrochloride, dobutamina clorhidrato spanish, 4-2-4-4-hydroxyphenyl butan-2-ylamino ethyl benzene-1,2-diol hydrochloride, +--4-2-3-p-hydroxyphenyl-1-methylpropyl amino ethyl pyrocatechol hydrochloride, 1,2-benzenediol, 4-2-3-4-hydroxyphenyl-1-methylpropyl amino ethyl-, hydrochloride, +-
PubChem CID 65324
ChEBI CHEBI:4671
IUPAC-Name hydrogen 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol chloride
SMILES [H+].[Cl-].CC(CCC1=CC=C(O)C=C1)NCCC1=CC=C(O)C(O)=C1

Spezifikation

Chemischer Name oder Material Dobutamine hydrochloride
Schmelzpunkt 184°C to 186°C
Farbe Weiß
Menge 250 mg
Merck Index 14,3395
Löslichkeitsinformationen Soluble in water or ethanol with warming; Also soluble in methanol
Formelmasse 337.85
Physikalische Form Pulver

RUO – Research Use Only

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