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  6. Invitrogen™ Human DNA-PK Native Protein

Invitrogen™ Human DNA-PK Native Protein

Codice prodotto. 15428803
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Quantità:
1 mg
10 μg
100 μg
Dimensione della confezione:
100µg
10µg
Pezzo
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Codice prodotto. Quantità Dimensione della confezione
15428803 10 μg 10µg
15117975 100 μg 100µg
15378517 1 mg Pezzo
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Codice prodotto. 15428803 Fornitore Invitrogen™ N. del fornitore PV5866
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Verfügbar ab: 02-12-2026
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Descrizione

Native Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Native human protein purified from MOLT-4 cells. No special measures were taken to activate this kinase. Protein Form: Full Length.

DNA-PK is a heterotrimeric, DNA-dependent protein kinase that initiates signaling cascades in response to DNA damage. DNA-PK is an atypical kinase, closely related to the PI3 kinases, and is often potently inhibited by small molecules designed to target PI3 kinases. DNA-PK encodes a component of the mediator complex, a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for DNA-PK.
TRUSTED_SUSTAINABILITY

Specifica

Numero di accesso P78527
Concentrazione Conc. Not Determined
Da utilizzare con (applicazione) Kinase Assay
Formulazione 25mM HEPES with 10mM MgCl2, 50mM KCl, 1mM DTT, 0.2mM EDTA, 10% glycerol and no preservative; pH 7.5
ID gene (immissione) 5591
Peso molecolare 600 kDa
Nome Human DNA-PK
Intervallo di pH 7.5
Quantità 10 μg
Requisiti di stoccaggio -80°C, Avoid Freeze/Thaw Cycles
Status giuridico RUO
Alias gene AI326420; AU019811; DNA-dependent protein kinase catalytic subunit; DNAPDcs; DNAPK; DNA-PK catalytic subunit; DNA-PKcs; DNPK1; DOXNPH; doxorubicin nephropathy; dxnph; hyper-radiosensitivity of murine scid mutation, complementing 1; HYRC; HYRC1; I79_017613; IMD26; p350; p460; Prkdc; protein kinase, DNA activated, catalytic polypeptide; protein kinase, DNA-activated, catalytic polypeptide; scid; severe combined immunodeficiency; slip; Xrcc7
Nome comune DNA-PK
Simbolo del gene PRKDC
Famiglia chinasi PIKK Kinase Family
Product Type Protein
Coniugato Unconjugated
Specie Human
Sequenza Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Assay Entry Biochemical terbium phospho-specific activity
Kinase Group Ser⁄Thr Kinases: Atypical
Shipping Condition Dry Ice
System Compatibility LanthaScreen™
Target Entry DNAPK
Gene bersaglio DNA-Pk.
Famiglia di proteine Kinases & Inhibitors
Protein Form Full Length
Forma Liquid
Sottotipo di proteina Lipid Kinases
Research Category Signal Transduction
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