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Dexamethason, 96 %, Thermo Scientific™

Dexamethasone, CAS# 50-02-2, is a synthetic adrenal corticosteroid that shows potent anti-inflammatory activity.

Marke:  Thermo Scientific Acros 230302500

Additional Details : CAS : 50-02-2 Gewicht : 0.05025kg


Menge 250mg
Verpackung Glasflasche

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Artikelnummer. 10053130

  • 55.64 CHF / 250 Milligramm

Verfügbar ab: 15-07-2022
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Beschreibung

Beschreibung

This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Information

• Dexamethasone is a synthetic adrenal glucocorticoid that modulates carbohydrate metabolism, inhibits adrenocorticotropic hormone secretion, and has pronounced anti-inflammatory activity
• Dexamethasone can bind to specific nuclear steroid receptors, inhibiting pro-inflammatory signals, promoting anti-inflammatory signals, and interfering with NF-kB activation and apoptotic pathways

Applications

• It can be used to study apoptosis, cell signaling pathways, and gene expression
• This compound also shows adrenergic, antiemetic, and antineoplastic activities
• It has been used as an important regulator of cellular proliferation and differentiation in vitro human cell cultures
• Dexamethasone has been applied in culture media to promote the differentiation of adipose-derived stem cells into osteogenic tissue
• It is used in in vitro stimulation of primary normal human bronchial epithelial cells (NHBE) and airway smooth muscle (ASM)
• This compound is used for its ability to regulate T cell survival, growth, and differentiation.
• It can also inhibit the induction of nitric oxide synthase.

Spezifikation

Chemische Identifikatoren

50-02-2
392.47
UREBDLICKHMUKA-CXSFZGCWSA-N
5743
(8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluor-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-on
C22H29FO5
MFCD00064136
dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol
CHEBI:41879
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

Spezifikation

Dexamethasone
Weiß
0.5% max. (105°C, 3 hrs)
Authentic
MFCD00064136
15, 2945
250mg
UREBDLICKHMUKA-CXSFZGCWSA-N
(8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluor-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-on
392.47
95% min. (on dried substance)
392.46
96%
50-02-2
255.0°C to 261.0°C
96%
C22H29FO5
Glasflasche
dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol
Solubility in water: 10mg/100mL (25 c). Other solubilities: soluble in acetone,ethanol and chloroform
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
+ 75.00
5743
CHEBI:41879
Kristallpulver
(HPLC) Passes test
Videos
Sicherheit und Handhabung

Sicherheit und Handhabung

Produktidentifikator
  • Dexamethasone

Signalwort
  • Achtung

Gefahrenkategorie
  • Karzinogenität Kategorie 2

Gefahrenhinweis
  • H351-Kann vermutlich Krebs erzeugen.

Sicherheitshinweis
  • P280-Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz tragen.

Sicherheitsdatenblatt (SDS) Dokumentation
Zertifikate
Sonderangebote

Sonderangebote

RUO – Research Use Only