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DENND5A Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Thermo Scientific PA563049
Additional Details : Gewicht : 0.02000kg
Beschreibung
Immunogen sequence: SALWSHLLHY QDNRQRKLTS GSLSTSGILL DSERRKSDAS SLMPPLRISL IQD Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.
DENND5A (DENN domain-containing protein 5A) is a guanine nucleotide exchange factor (GEF) which activates RAB6A and RAB39A/RAB39B. It promotes the exchange of GDP to GTP by converting inactive GDP-bound Rab proteins to their active GTP form. DENND5A is also involved in the negative regulation of neurtie outgrowth. Mutations affecting this gene can result in epileptic encephalopathy, early infantile, 49 (EIEE49).Spezifikation
DENND5A | |
Polyclonal | |
Unconjugated | |
DENND5A | |
1500012B19Rik; AJ245569; AW496491; DENN domain containing 5A; DENN domain-containing protein 5A; DENN/MADD domain containing 5A; DENND5A; KIAA1091; mKIAA1091; ORF37; Rab6 interacting protein 1; rab6-interacting protein 1; RAB6IP1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
23258 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q6IQ26 | |
DENND5A | |
Recombinant protein corresponding to Human DENND5A | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only