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DENND1C Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Thermo Scientific PA560105
Additional Details : Gewicht : 0.02000kg
Beschreibung
Immunogen sequence: PSPPESPQIL APTKPNFDIA WTSQPLDPSS DPSSLEDPRA RPPKALLAER AHLQPREEPG ALNSPATPTS NCQKSQPSSR PRVADLKKCF E Highest antigen sequence identity to the following orthologs: Mouse - 47%, Rat - 45%.
Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.Spezifikation
| DENND1C | |
| Polyclonal | |
| Unconjugated | |
| DENND1C | |
| Connecdenn 3; DENN domain containing 1C; DENN domain-containing protein 1C; DENN/MADD domain containing 1C; DENND1C; FAM31C; family with sequence similarity 31, member C; Protein FAM31C | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 79958 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry | |
| 0.3 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q8IV53 | |
| DENND1C | |
| Recombinant protein corresponding to Human DENND1C | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only