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ACROBiosystems Cynomolgus CD3 delta Protein, His Tag

400.19 CHF - 2226.04 CHF

Spezifikation

Molekulargewicht 14.3 kDa
Quelle Cynomolgus CD3 delta, His Tag (CDD-C52H8) is expressed from human 293 cells (HEK293). It contains AA Phe 22 - Ala 105 (Accession # Q95LI8).
Immunogen Phe 22 - Ala 105
Lagerungsbedingungen -20°C
Gen-Alias CD3D,CD3-DELTA,T3D
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15826377
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ACROBiosystems
CDD-C52H8-100UG
100 μg
400.19 CHF
100 Mikrogramm
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15836377
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ACROBiosystems
CDD-C52H8-1MG
1 mg
2226.04 CHF
1 Milligramm
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Verfügbar ab: 11-04-2024
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Beschreibung

Beschreibung

CD3D is also known as CD3-DELTA, T3D, and is a single-pass type I membrane protein. CD3D is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. Defects in CD3D cause severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T-/B+/NK+ SCID) which is a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 14.3 kDa. The protein migrates as 26-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

14.3 kDa
Phe 22 - Ala 105
CD3D,CD3-DELTA,T3D
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>90% as determined by SDS-PAGE
Cynomolgus CD3 delta, His Tag (CDD-C52H8) is expressed from human 293 cells (HEK293). It contains AA Phe 22 - Ala 105 (Accession # Q95LI8).
-20°C
CD3 delta
Cynomolgus Monkey
PBS, pH7.4
HEK293
Bio-Markers and CD Antigens
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Sicherheitsdatenblatt (SDS)
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