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CTRP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 12209-1-AP-20UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16839783

  • 131.19 CHF / 20 Mikroliter

Verfügbar ab: 01-07-2022
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Beschreibung

Beschreibung

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.
Spezifikation

Spezifikation

CTRP1
Polyclonal
Unconjugated
C1QTNF1
C1QTNF1, CTRP1, GIP, ZSIG37
Rabbit
Antigen Affinity Chromatography
RUO
114897, 303701, 56745
Antibody
IgG
Immunofluorescence, Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q5XIG2, Q9BXJ1, Q9QXP7
C1qtnf1
CTRP1 Fusion Protein Ag2854
20 μL
Primary
Rat, Mouse, Human
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote