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Cripto Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA534476
Additional Details : Gewicht : 0.01000kg
Beschreibung
A suggested positive control is 293 cell lysate. PA5-34476 can be used with blocking peptide PEP-1518.
Cripto (TDGF1) is a GPI-anchored cell membrane proetin involved in Nodal signaling. Cell associated TDGF1 acts as a a Nodeal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulated Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.Spezifikation
| Cripto | |
| Polyclonal | |
| Unconjugated | |
| TDGF1 | |
| CR; CR1; CRGF; CRIPTO; cripto growth factor; Cripto-1; cripto-1 growth factor; Cripto-3; epidermal growth factor-like Cripto protein; epidermal growth factor-like cripto protein CR1; Tdgf1; TDGF2; teratocarcinoma-derived growth factor; teratocarcinoma-derived growth factor 1; TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR) | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 21667, 680246, 6997 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| P13385, P51865 | |
| TDGF1 | |
| A 17 amino acid peptide near the amino terminus of human TDGF1 | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |