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  6. Invitrogen™ Collagen IV Monoclonal Antibody (1042), eBioscience™, Invitrogen™

Invitrogen™ Collagen IV Monoclonal Antibody (1042), eBioscience™, Invitrogen™

Codice prodotto. 17100822
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Quantità:
2 mg
10 mg
Dimensione della confezione:
10mg
2mg
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Codice prodotto. Quantità Dimensione della confezione
17100822 2 mg 2mg
17110822 10 mg 10mg
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Codice prodotto. 17100822 Fornitore Invitrogen™ N. del fornitore 14987137
  • ONLINE EXCLUSIVE PRICE
    1784.00 CHF
    1373.68 CHF / 2 Milligramm
    Sparen 410.32 CHF
    23% Rabatt
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Verfügbar ab: 15-12-2026
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Descrizione

Mouse Monoclonal Antibody

Description: This monoclonal antibody 1042 recognizes human collagen Type IV. Collagens are the main components of the extracellular matrix and provide the tensile strength to tissues. There are four main types of collagen (I, II, III and IV) which contribute to the connective tissue. Expression of type IV is restricted to the basal lamina. It contains two alpha-1 and one alpha-2-like chains. Collagen Type IV is associated with disorders such as Alport syndrome and Goodpasture's syndrome. Applications Reported: This 1042 antibody has been reported for use in immunoprecipitation, western blotting, immunohistochemical staining of frozen (IHC-F) and formalin-fixed paraffin embedded (IHC-P) tissue sections. Applications Tested: This 1042 antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded (FFPE) tissue with low pH antigen retrieval. This can be used at less than or equal to 5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

Collagen IV is a type of collagen protein that is a major component of the basement membrane in various tissues, including the kidneys, lungs, and skin. It forms a network-like structure that provides support and stability to the surrounding tissue. Collagen IV is composed of three alpha chains, which are encoded by the COL4A1, COL4A2, and COL4A3 genes. Mutations in these genes can lead to various genetic disorders, such as Alport syndrome and Goodpasture syndrome, which affect the kidneys and lungs, respectively.
TRUSTED_SUSTAINABILITY

Specifica

Antigene Collagen IV
Applicazioni Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classificazione Monoclonal
Clone 1042
Concentrazione 0.5 mg/mL
Coniugato Unconjugated
Formulazione PBS with 0.09% sodium azide; pH 7.2
Gene COL4A6
N. accesso geni P02462, P08572, P29400, P53420, Q01955, Q14031
Alias gene [a]3(IV); [a]4(IV); alpha 1 type IV collagen; alpha type IV collagen basement membrane; alpha1(IV) collagen; alpha-2 collagen type IV; alpha-3 type IV collagen; alpha3(IV); Arresten; Bru; BSVD; CA44; Canstatin; Col4a1; Col4a-1; COL4A1 NC1 domain; Col4a2; Col4a-2; COL4A3; col4a4; Collagen 4; Collagen alpha-1(IV) chain; collagen alpha-2(IV) chain; Collagen alpha-3(IV) chain; collagen alpha-4(IV) chain; collagen IV, alpha-1 polypeptide; collagen IV, alpha-3 polypeptide; Collagen IV, alpha-4 polypeptide; collagen of basement membrane, alpha-1 chain; collagen of basement membrane, alpha-4 chain; collagen type IV alpha 1 chain; collagen type IV alpha 2; collagen type IV alpha 2 chain; collagen type IV alpha 3 chain; collagen type IV alpha 4 chain; collagen type IV alpha3 chain; collagen, type IV, alpha 1; collagen, type IV, alpha 2; collagen, type IV, alpha 3; collagen, type IV, alpha 3 (Goodpasture antigen); collagen, type IV, alpha 4; Del(8)44H; Del(8)Bru44H; E130010M05Rik; Goodpasture antigen; ICH; LOW QUALITY PROTEIN: collagen alpha-1(IV) chain; LOW QUALITY PROTEIN: collagen alpha-3(IV) chain; LOW QUALITY PROTEIN: collagen alpha-4(IV) chain; POREN2; procollagen alpha1(IV); procollagen, type IV, alpha 1; procollagen, type IV, alpha 2; procollagen, type IV, alpha 3; procollagen, type IV, alpha 4; RATOR; Raw; retinal anterior wiring; Svc; tumstatin; Type IV Collagen
Simboli geni COL4A1, COL4A2, Col4a3, COL4A4, COL4A5, COL4A6
Specie ospite Mouse
Metodo di purificazione Affinity chromatography
Quantità 2 mg
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 1282, 1284, 1285, 1286, 1287, 1288
Target Species Human
Content And Storage 4°C
Product Type Antibody
Forma Liquid
Isotype IgG2b κ
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