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CLCN1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 18595-1-AP-20UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16838554

  • 131.19 CHF / 20 Mikroliter

Verfügbar ab: 28-06-2022
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Beschreibung

Beschreibung

The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. CLC1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC2 is highly expressed in the epithelia of several organs including lung, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis. CLC3 expression is particularly abundant in neuronal tissue, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC5 lead to Dents disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.
Spezifikation

Spezifikation

CLCN1
Polyclonal
Unconjugated
CLCN1
Chloride channel protein 1, ClC 1, CLC1, CLCN1
Rabbit
Antigen Affinity Chromatography
RUO
1180
Antibody
IgG
ELISA
0.15 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P35523
CLCN1
CLCN1 Fusion Protein Ag13336
20 μL
Primary
Human
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote