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Invitrogen™ Claudin 5 Monoclonal Antibody (4C3C2), Alexa Fluor™ 488

Codice prodotto. 10237304
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Quantità:
100 μg
Dimensione della confezione:
Pezzo
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Codice prodotto. Quantità Dimensione della confezione
10237304 100 μg Pezzo
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Codice prodotto. 10237304 Fornitore Invitrogen™ N. del fornitore 352588
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Mouse Monoclonal Antibody

Reactivity has been confirmed with rat, human and mouse Claudin-5 using rat lung, mouse kidney, mouse small intestine, mouse lung homogenates, human colon tissue, and CACO-2 human cell line. This antibody reacts specifically with the ~ 22-24 kDa endogenous Claudin-5 protein. Excitation/Peak Emission (nm): 495/519.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
TRUSTED_SUSTAINABILITY

Specifica

Antigene Claudin 5
Applicazioni ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Classificazione Monoclonal
Clone 4C3C2
Concentrazione 0.5 mg/mL
Coniugato Alexa Fluor 488
Formulazione PBS with 4mg/mL BSA and 0.1% sodium azide; pH 7.4
Gene CLDN5
N. accesso geni O00501, O54942, Q9JKD6
Alias gene AI854493; AWAL; BEC1; Brain endothelial cell clone 1 protein; claudin 5; claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); claudin-5; claudin-5 protein; Cldn5; CPETRL1; lung-specific membrane protein; MBEC1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome; Unknown (protein for MGC:138054)
Simboli geni CLDN5
Specie ospite Mouse
Immunogeno Synthetic peptide derived from the mouse Claudin-5 protein.
Metodo di purificazione Protein A
Quantità 100 μg
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 12741, 65131, 7122
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Forma Liquid
Isotype IgG1
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