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Invitrogen™ Claudin 5 Monoclonal Antibody (4C3C2), Alexa Fluor™ 488
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Produktkode 10237304
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Menge:
100 μg
Förpackningsstorlek:
1 Stück
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Produktkode Menge Förpackningsstorlek
10237304 100 μg 1 Stück
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Produktkode 10237304 missing translation for 'mfr' Invitrogen™ missing translation for 'supplierNo' 352588
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Beskrivelse

Mouse Monoclonal Antibody

Reactivity has been confirmed with rat, human and mouse Claudin-5 using rat lung, mouse kidney, mouse small intestine, mouse lung homogenates, human colon tissue, and CACO-2 human cell line. This antibody reacts specifically with the ~ 22-24 kDa endogenous Claudin-5 protein. Excitation/Peak Emission (nm): 495/519.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Claudin 5
Anwendungen ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Klassifikation Monoclonal
Klon 4C3C2
Konzentration 0.5 mg/mL
Konjugat Alexa Fluor 488
Zusammensetzung PBS with 4mg/mL BSA and 0.1% sodium azide; pH 7.4
Gen CLDN5
Gen-Zugriffsnummer O00501, O54942, Q9JKD6
Gen-Alias AI854493; AWAL; BEC1; Brain endothelial cell clone 1 protein; claudin 5; claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); claudin-5; claudin-5 protein; Cldn5; CPETRL1; lung-specific membrane protein; MBEC1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome; Unknown (protein for MGC:138054)
Gensymbole CLDN5
Wirtsspezies Mouse
Immunogen Synthetic peptide derived from the mouse Claudin-5 protein.
Reinigungsverfahren Protein A
Menge 100 μg
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 12741, 65131, 7122
Zielspezies Human, Mouse, Rat
Inhalt und Lagerung 4°C
Produkttyp Antibody
Form Liquid
Isotype IgG1
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