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Invitrogen™ Chromogranin A Polyclonal Antibody
Rabbit Polyclonal Antibody
Marke: Invitrogen™ PA5110826
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Beschreibung
Immunogen sequence: NSPMNKGDTE VMKCIVEVIS DTLSKPSPMP VSQECFETLR GDERILSILR HQNLLKELQD LALQGAKERA HQQKKHSGFE DELSEVLENQ SSQAELKEAV EEPSSKDVME KREDSKEAEK SGEATDGARP QALPEPMQES K Highest antigen sequence indentity to the following orthologs: Rat - 64%, Mouse - 62%.
Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
Spezifikation
| Chromogranin A | |
| Polyclonal | |
| Unconjugated | |
| Chga | |
| AL-11; AL26; Beta-granin; betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; CHGA; ChrA; chromofungin; chromogranin A; chromogranin A (parathyroid secretory protein 1); chromogranin A precursor; chromogranin-A; CTNNB; DKFZp686D02253; EA-92; ER-37; ES-43; FLJ25606; FLJ37923; GE-25; GR-44; GV-19; LF-19; LOW QUALITY PROTEIN: chromogranin-A; MGC105435; Pancreastatin; Parastatin; parathyroid secretory protein 1; p-Glu serpinin precursor; pituitary secretory protein I; Serpinin; Serpinin-RRG; SL21; SP-I; SS-18; Vasostatin I; Vasostatin II; Vasostatin-1; Vasostatin-2; WA-8; WE-14 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 1113 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.10 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P10645 | |
| Chga | |
| Recombinant Protein corresonding to Human Chromogranin A. Recombinant protein control fragment (Product #RP-96603). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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