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Invitrogen™ Human CDK1/cyclin A2, GST Tag Recombinant Protein
Human CDK1/cyclin A2, GST Tag Recombinant Protein
574.00 CHF
Spezifikation
| Zur Verwendung mit (Anwendung) | Kinase Assay |
|---|---|
| Molekulargewicht | 60.4/74.8 kDa |
| Spezies | Human |
| Rekombinant | Recombinant |
| Proteinmarkierung | GST Tag |
Beschreibung
CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Spezifikation
| Kinase Assay | |
| Human | |
| GST Tag | |
| Serine/Threonine Kinase | |
| Liquid |
| 60.4/74.8 kDa | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. |
|
| Baculovirus |