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  6. Invitrogen™ CD88 (C5aR1) Monoclonal Antibody (20/70), PE, eBioscience™, Invitrogen™

Invitrogen™ CD88 (C5aR1) Monoclonal Antibody (20/70), PE, eBioscience™, Invitrogen™
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Artikelnummer. 16596900
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Menge:
100 μg
25 μg
Packungsgröße:
100 Mikrogramm
25 Mikrogramm
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16596900 100 μg 100 Mikrogramm
16586900 25 μg 25 Mikrogramm
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Artikelnummer. 16596900 Lieferant Invitrogen™ Lieferanten-Nr. 12088282

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Beschreibung

Rat Monoclonal Antibody

Description: This 20/70 monoclonal antibody recognizes mouse CD88 also known as C5aR1. CD88 is a complement receptor widely expressed on cells of the myeloid lineage. Clone 20/70 has been reported to block the binding of C5a to murine CD88. Applications Reported: This 20/70 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 20/70 antibody has been tested by flow cytometric analysis of mouse bone marrow cells. This may be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser

CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known. C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production. CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex. Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen CD88 (C5aR1)
Anwendungen Flow Cytometry
Klassifikation Monoclonal
Klon 20/70
Konzentration 0.2 mg/mL
Konjugat PE
Zusammensetzung PBS with 0.09% sodium azide; pH 7.2
Gen C5AR1
Gen-Zugriffsnummer P30993
Gen-Alias anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1
Gensymbole C5AR1
Wirtsspezies Rat
Immunogen RBL-2H3 transfected cells expressing murine C5aR.
Reinigungsverfahren Affinity chromatography
Menge 100 μg
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 12273
Zielspezies Mouse
Inhalt und Lagerung 4°C, store in dark, DO NOT FREEZE!
Produkttyp Antibody
Form Liquid
Isotype IgG2b κ
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