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CD81 Mouse anti-Human, APC, Clone: JS-81, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 561958
Beschreibung
JS-81 identifies the newly clustered CD81 antigen, a 26 kDa, type III transmembrane protein (also known as TAPA-1) that is involved in cell growth and signal transduction. CD81 has a very broad cellular distribution, being expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin. MAbs to CD81 have been shown to have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. Immunoprecipitation studies reveal that CD81 is a component of a multimolecular complex which can include the Leu13 molecule, and the CD19 and CD21 molecules in B cells. MAbs to CD81 are reported to induce homotypic cell aggregation.
Spezifikation
| CD81 | |
| Monoclonal | |
| APC | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Affinity Purified | |
| RUO | |
| Canine, Human, Rabbit | |
| IgG1 κ |
| Flow Cytometry | |
| JS-81 | |
| TAPA-1 | |
| Mouse | |
| 25 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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For Research Use Only.