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CD7 Monoclonal Antibody (eBio124-1D1 (124-1D1)), Super Bright™ 436, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Marke:  Invitrogen 62007942

Additional Details : Gewicht : 0.01000kg

Artikelnummer. 15983334

  • 363.00 CHF / 100 Stück
Verfügbar ab: 11-04-2024
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Beschreibung

Beschreibung

Description: The eBio124-1D1 monoclonal antibody reacts with human CD7, also known as gp40 and Leu9. CD7, a 40 kD receptor, is a member of the immunoglobulin gene superfamily. The N-terminal amino acid sequence (aa1-107) is highly homologous to Ig kappa light chain sequence; while the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T lymphocytes, and T cell leukemias. It is also found on natural killer cells, a small suppopulation of normal B cells and on maligant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity, as measured by calcium flux, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. A clonogenic subpopulation of human CD34(+) CD38(-) cord blood cells that express CD45RA and HLA-DR and high levels of the CD7 has been reported. These cells possess the capacity for lymphopoiesis. They can generate B-cells, natural killer cells, and dendritic cells but do not possess the capacity to develop into myeloid cells or erythroid cells. The CD7(+) phenotype distinguishes primitive human lymphoid progenitors from pluripotent stem cells.

CD7 Monoclonal antibody specifically detects CD7 in Human samples. It is validated for Flow Cytometry.
Spezifikation

Spezifikation

CD7
Monoclonal
5 μL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
P09564
CD7
Affinity chromatography
RUO
924
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
eBio124-1D1 (124-1D1)
Super Bright 436
CD7
Cd7; CD7 antigen; CD7 antigen (p41); Cd7 molecule; GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41
Mouse
100 Tests
Primary
Human
Antibody
IgG1 κ
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote