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CD55 Monoclonal Antibody (RIK0-3), Biotin, Invitrogen™
Armenian Hamster Monoclonal Antibody
Marke: Invitrogen MA517676
Additional Details : Gewicht : 0.01000kg
Beschreibung
MA5-17676 targets DAF in ELISA, FACS, and WB applications and shows reactivity with Mouse samples. The MA5-17676 immunogen is gPI-DAF transfected CHO cells.
CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can regulate complement when bound to CD97. In tumors, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis. CD55 is a 70 kDa glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail. In other cells, the apparent molecular weight is somewhat larger for CD55 and has a substantial content of O-glycans. CD55 binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways. CD55 carries the Cromer related blood group antigens. Two alternatively spliced transcripts encoding CD55 have been identified, and the predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. CD55 has been studied to have a role in prostate cancer growth and survival.Spezifikation
CD55 | |
Monoclonal | |
0.1 mg/mL | |
PBS with 4-5mg/mL BSA and 0.02% sodium azide | |
Q61475 | |
CD55 | |
GPI-DAF transfected CHO cells | |
100 μg | |
Primary | |
Mouse | |
Antibody | |
IgG |
ELISA, Flow Cytometry, Western Blot | |
RIK0-3 | |
Biotin | |
CD55 | |
CD55; CD55 antigen; CD55 molecule (Cromer blood group); CD55 molecule, decay accelerating factor for complement; CD55 molecule, decay accelerating factor for complement (Cromer blood group); Cd55a; Complement decay-accelerating factor; complement decay-accelerating factor, GPI-anchored; complement-glycosylphosphatidylinositol; CR; CROM; Cromer blood group; Daf; Daf1; DAF-GPI; decay accelarating factor 1; decay accelerating factor 1; decay accelerating factor GPI-form; decay-accelarating factor; glycosylphophatidylinositol-anchored form; GPI anchor addition signal; GPI-DAF; RP11-357P18.1; TC | |
Armenian Hamster | |
Protein G | |
RUO | |
13136 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |