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CD4 Rat anti-Mouse, FITC, Clone: GK1.5, BD

Rat Monoclonal Antibody

99.55 CHF - 283.00 CHF

Spezifikation

Antigen CD4
Isotyp IgG2b, κ
Immunogen Mouse CTL clone V4
Zusammensetzung Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Konjugat FITC
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Produkte 3
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15831379
Unterlagen ansehen
BD Biosciences
561828
25μg
121.00 CHF
1 Stück
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Verfügbar ab
02-07-2021
Zum Warenkorb hinzufügen
 
15818878
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BD Biosciences
557307
0.1mg
99.55 CHF
1 Stück
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Verfügbar ab
29-06-2021
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15847358
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BD Biosciences
553729
0.5mg
283.00 CHF
1 Stück
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Verfügbar ab
29-06-2021
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Beschreibung

Beschreibung

The GK1.5 monoclonal antibody specifically binds to the mouse CD4 (L3T4) differentiation antigen. CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells), and a subset of NK-T cells. In addition, CD4 has also been reported to be detectable on pluripotent hematopoietic stem cells, bone marrow myeloid and B-lymphocyte precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells. CD4 has also been reported to be expressed on the plasma membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm. CD4 is an antigen coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck. The GK1.5 antibody reportedly blocks binding of the RM4-5 and H129.19, but not RM4-4 mouse CD4-specific antibodies.

Spezifikation

Spezifikation

CD4
Mouse CTL clone V4
FITC
Immunology
Rat
Affinity Purified
Monoclonal
Cd4; CD4 antigen; L3T4; Ly-4; T-cell surface antigen T4/Leu-3
IgG2b, κ
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Primary
Flow Cytometry
RUO
GK1.5
0.5mg/mL
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Sicherheitsdatenblatt (SDS)

For Research Use Only.