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CD365 (TIM1) Rat anti-Mouse, Biotin, Clone: RMT1-4, eBioscience™

Rat Monoclonal Antibody

Marke:  Affymetrix eBioscience 13-5861-85

Additional Details : Gewicht : 0.25000kg

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Artikelnummer. 15229879

  • 403.00 CHF / 500 Mikrogramm


Verfügbar ab
10-08-2020
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Beschreibung

Beschreibung

It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered. HAVCR1, a 359 A.A Class 1 integral membrane glycoprotein, is used by Hepatitis A virus to infect humans. It consists of a conserved N-terminal Cys-rich region, IgV (Immunoglobulin Variable region like) domain and a TSP-rich mucin domain in the extracellular region followed by a highly conserved tyrosine kinase phosphorylation motif in the cytoplasmic region. HAVCR1 is expressed on terminally differentiated CD4+ Th2 cells and regulates cytokine production. It plays an important role in the regulation of immune responses in the development of asthma and allergic responses. Its expression is critically upregulated in dedifferentiated kidney cells, thus indicating a possible role in regeneration of proximal tubule epithelium in Kidneys. HAVCR1 has shown to be upregulated in renal carcinomas, suggesting its role in tumor progression and metastasis.
Spezifikation

Spezifikation

CD365 (TIM1)
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q5QNS5
HAVCR1, TIM-1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
RMT1-4
Biotin
Havcr1
Liquid
Havcr1
IgG2b, kappa
500 μg
4° C, store in dark, DO NOT FREEZE!
Primary
171283
Videos
Dokumentation

For Research Use Only.