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CD321 (F11R) Mouse anti-Human, Clone: CSTEM27, eBioscience™

Mouse Monoclonal Antibody

Marke:  Invitrogen 14-3219-82

Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15805353

  • 116.00 CHF / 100 Mikrogramm


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von Anbieter 03-04-2019
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Beschreibung

Beschreibung

CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintece of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.
Spezifikation

Spezifikation

CD321 (F11R)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q9Y624
F11 R, JAMA, junctional adhesion molecule A, JAM-1, JAM-A
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunoblot, Immunocytochemistry, Western Blot
CSTEM27
Unconjugated
F11R
Liquid
F11R
IgG2a, kappa
100 μg
4° C, do not freeze
Primary
50848
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