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CD3 Mouse anti-Rat, FITC, Clone: G4.18, BD

Mouse Monoclonal Antibody

331.00 CHF - 520.00 CHF

Spezifikation

Antigen CD3
Isotyp IgG3, κ
Immunogen PHA-stimulated rat lymph node and spleen cells
Zusammensetzung Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Konjugat FITC
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15839848
Unterlagen ansehen
BD Biosciences
559975
0.1mg
331.00 CHF
1 Stück
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Verfügbar ab
29-06-2021
Zum Warenkorb hinzufügen
 
15817878
Unterlagen ansehen
BD Biosciences
554832
0.5mg
520.00 CHF
1 Stück
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Verfügbar ab
02-07-2021
Zum Warenkorb hinzufügen
 
Beschreibung

Beschreibung

The G4.18 antibody reacts with the T-cell receptor-associated CD3 cell-surface antigen found on thymocytes, peripheral T lymphocytes, and dendritic epidermal T cells. It has been reported that CD3 expression is down-regulated within 24 hours in concanavalin A-stimulated rat T cells, and soluble mAb inhibits the allogeneic mixed-lymphocyte proliferative response and cell-mediated cytotoxicity to allogeneic target cells. In vivo treatment with G4.18 mAb prevents cardiac and skin allograft rejection, resulting in donor-specific tolerance. Pre-incubation of splenocytes with the alternate anti-rat CD3 monoclonal antibody, 1F4 (Cat. No. 556970), blocks staining with mAb G4.18.

This antibody is routinely tested by flow cyometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Spezifikation

Spezifikation

CD3
PHA-stimulated rat lymph node and spleen cells
FITC
Flow Cytometry
RUO
G4.18
0.5mg/mL
IgG3, κ
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Primary
Murine
Affinity Purified
Monoclonal
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Sicherheitsdatenblatt (SDS)

For Research Use Only.