missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CD279 (PD-1) Monoclonal Antibody (J43), Super Bright™ 645, eBioscience™, Invitrogen™
Armenian Hamster Monoclonal Antibody
Marke: Affymetrix eBioscience 64-9985-82
Additional Details : Gewicht : 0.01000kg
Beschreibung
Armenian Hamster Monoclonal Antibody
Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "e;danger signals"e; such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.Spezifikation
CD279 (PD-1) | |
Monoclonal | |
0.2 mg/mL | |
PBS with BSA and 0.09% sodium azide; pH 7.2 | |
Q02242 | |
Pdcd1 | |
Affinity chromatography | |
RUO | |
18566 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
J43 | |
Super Bright 645 | |
Pdcd1 | |
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2 | |
Armenian Hamster | |
100 μg | |
Primary | |
Mouse | |
Antibody | |
IgG |