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CD223 (LAG-3) Monoclonal Antibody (3DS223H), eFluor™ 450, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
184.00 CHF - 508.00 CHF
Spezifikation
Klon | 3DS223H |
---|---|
Konzentration | 5 μL/Test |
Anwendungen | Flow Cytometry |
Klassifikation | Monoclonal |
Konjugat | eFluor 450 |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15319965
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Affymetrix eBioscience
48-2239-42 |
100 Tests |
508.00 CHF
100 Stück |
Lager vorrätigLoggen Sie sich ein, um den Lagerbestand zu sehen
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15529736
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Affymetrix eBioscience
48-2239-41 |
25 Tests |
Dieser Artikel wurde eingestellt und ist leider nicht mehr verfügbar. Sehen Sie sich das Produkt an, um alternative Produktvorschläge zu sehen oder kontaktieren Sie unseren Technischen Support unter 056 618 41 11. |
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Beschreibung
Description: This 3DS223H monoclonal antibody recognizes human CD223 also known as Lymphocyte Activation Gene 3 (LAG-3). LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells). This 3DS223H antibody will recognize a formaldehyde-fixed epitope. Applications Reported: This 3DS223H antibody has been reported for use in flow cytometric analysis. Applications Tested: This 3DS223H antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. eFluor™ 450 is an alternative to Pacific Blue™. eFluor™ 450 emits at 445 nm and is excited with the Violet laser (405 nm).
LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).Spezifikation
3DS223H | |
Flow Cytometry | |
eFluor 450 | |
Mouse | |
Human | |
3902 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
P18627 | |
LAG3 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
LAG3 |
For Research Use Only.