CD215 (IL-15Ra) Mouse anti-Human, Clone: eBioJM7A4, eBioscience™
Mouse Monoclonal Antibody
Marke: Affymetrix eBioscience 14-7159-80
Additional Details : Gewicht : 0.01000kg
BeschreibungCell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.
|PBS with 0.09% sodium azide; pH 7.2|
|IL-15RA, Interleukin-15 receptor subunit alpha, IL15RA, CD215|
|Flow Cytometry, Immunoprecipitation, Western Blot|
For Research Use Only.