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CD185 (CXCR5) Monoclonal Antibody (MU5UBEE), Super Bright™ 436, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 62-9185-42

248.01 CHF gültig bis 2024-03-29
Benutzen Sie den Promotions-Code "21615" um Ihren Promotions-Preis zu erhalten.



Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15983444

  • 372.00 CHF / 100 Stück
Verfügbar ab: 11-04-2024
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Beschreibung

Beschreibung

Description: The MU5UBEE monoclonal antibody reacts with human and non-human primate CD185. CD185, which is also known as C-X-C chemokine receptor 5 (CXCR5) and Burkitt lymphoma receptor 1 (BLR1), is a seven transmembrane G protein-coupled receptor originally identified in Burkitt's lymphoma. In peripheral blood, CD185 is expressed on B cells, CD4+ T cells (but not Th1 or Th2 cells), as well as on a subpopulation of memory (CD45RO+) T cells. Circulating CD185+ T cells are in a resting state and migrate to the lymph nodes due to expression of CCR7 and CD62L. In tonsil, CD185 is expressed on nearly all CD4+ cells together with CD45RO and activation markers such as CD69 and ICOS. Tonsillar CD185+ cells have been shown to induce antibody production when co-cultured with B cells, thus supporting their role in providing help to B cells. Furthermore, this chemokine receptor plays a critical role in lymphocyte trafficking, in particular T cell migration into the B cell follicles of germinal centers in response to CXCL13, making CD185 an established marker of follicular helper T cells. Applications Reported: This MU5UBEE antibody has been reported for use in flow cytometric analysis. Applications Tested: This MU5UBEE antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (1.0 μg) per test.

CD185 (CXCR5) Monoclonal antibody specifically detects CD185 (CXCR5) in Human, Non-human Primate, Rhesus Monkey samples. It is validated for Flow Cytometry.
Spezifikation

Spezifikation

CD185 (CXCR5)
Monoclonal
5 μL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
P32302
CXCR5
N-terminal extracellular domain
100 Tests
Primary
Human, Non-human Primate, Rhesus Monkey
Antibody
IgG2b κ
Flow Cytometry
MU5UBEE
Super Bright 436
CXCR5
Blr1; Blr-1; Burkitt lymphoma receptor 1; burkitt lymphoma receptor 1 homolog; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5); Burkitt lymphoma receptor 1, GTP-binding protein; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD185; CD185 antigen; chemochine (C-X-C motif) receptor 5; chemokine (C-X-C motif) receptor 5; CXC; C-X-C chemokine receptor type 5; CXC motif chemokine; C-X-C motif chemokine receptor 5; CXCR5; CXC-R5; CXCR-5; EGK_06966; Fusin; Gpcr6; GPR9; HUMSTR; LESTR; MDR15; MDR-15; Monocyte-derived receptor 15; neurolymphatic receptor; NLR
Mouse
Affinity chromatography
RUO
643, 701792
4° C, store in dark, DO NOT FREEZE!
Liquid
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote