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CD161 Mouse anti-Human, FITC, Clone: DX12, BD

Mouse Monoclonal Antibody

490.00 CHF - 720.00 CHF

Spezifikation

Antigen CD161
Klon DX12
Anwendungen Flow Cytometry
Klassifikation Monoclonal
Konjugat FITC
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15825918
Unterlagen ansehen Aktionsdetails
BD Biosciences
340536
50 Tests
720.00 CHF
1 Stück
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Verfügbar ab: 22-04-2024
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15808638
Unterlagen ansehen Aktionsdetails
BD Biosciences
556080
100 Tests
490.00 CHF
1 Stück
Alternative Produkte anzeigen
Sparen Sie bis zu 
»
Verfügbar ab: 22-04-2024
Sie sich ein, um den Lagerbestand zu sehen
Zum Warenkorb hinzufügen
 
Beschreibung

Beschreibung

The DX12 monoclonal antibody specifically binds to human CD161 which is also known as Natural killer cell surface protein P1A (NKR-P1A). CD161 is encoded by the KLRB1 (Killer cell lectin-like receptor subfamily B member 1) gene. CD161 is a member of the C-type lectin superfamily and is also referred to as C-type lectin domain family 5 member B (CLEC5B). CD161 is a 80 kDa disulfide-linked homodimer, type II membrane glycoprotein. CD161 is expressed mostly on NK cell populations and on subsets of CD4+ and CD8+ αβ T cells, NKT cells and γδ T cells. Reports indicate that CD161 is expressed preferentially on CD45RO+ T cells, however, it can be found on a subset of thymocytes and fetal liver T cells. Its function has not been fully elucidated, but reports indicate that NKR-P1A may serve as a specific receptor for some NK cell targets. The DX12 antibody can reportedly inhibit spontaneous cytotoxicity mediated by certain NK cell clones.

Spezifikation

Spezifikation

CD161
Flow Cytometry
FITC
RUO
Human
IgG1 κ
DX12
Monoclonal
Mouse
Immunology
Human NKR-P1A Transfected Mouse Fibroblasts
Primary
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Product Certifications

For Research Use Only.