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CD16 Mouse anti-Human, Alexa Fluor 647, Clone: 3G8, BD

Mouse Monoclonal Antibody

356.00 CHF - 555.00 CHF

Spezifikation

Antigen CD16
Klon 3G8
Anwendungen Flow Cytometry
Klassifikation Monoclonal
Konjugat Alexa Fluor 647
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15891269
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BD Biosciences
561724
25 Tests
356.00 CHF
1 Stück
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Verfügbar ab: 23-04-2024
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15819008
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BD Biosciences
557710
100 Tests
555.00 CHF
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Description

Description

The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcγRIII), a human NK cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes. The 3G8 antibody is reported (Vossebeld et al., 1997) to increase intracellular calcium levels in human neutrophils by interacting with bothFcγRIIa and FcγRIIIb molecules. This antibody has also been reported to induce homotypic neutrophil aggregation.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

Specifications

CD16
Flow Cytometry
Alexa Fluor 647
RUO
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
IgG1 κ
Affinity Purified
FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3
3G8
Monoclonal
Mouse
Baboon, Cynomolgus, Human, Rhesus Monkey
Human polymorphonuclear leukocytes
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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